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Supplement Name Description More Info

ABx Support™ is a carefully researched blend of the non- pathogenic yeast Saccharomyces boulardii with Lactobacillus rhamnosus, Bifidobacterium bifidum, and Bifidobacterium breve, probiotic microorganisms documented to support the normal gastrointestinal microbiota.* This hypoallergenic formulation is provided in vegetarian capsules in bottles of 28 capsules, a convenient 14-day supply for concurrent use during antibiotic therapy, or larger bottles of 60 capsules.

ABx Support™ is a carefully researched blend of the non- pathogenic yeast Saccharomyces boulardii with Lactobacillus rhamnosus, Bifidobacterium bifidum, and Bifidobacterium breve, probiotic microorganisms documented to support the normal gastrointestinal microbiota.*

Alpha-ketoglutaric acid (AKG) is a ketone derivative of the organic compound glutaric acid. It is a precursor to glutamic acid, the non-essential amino acid involved in protein synthesis and the regulation of blood glucose metabolism.* In combination with L-glutamate, AKG can help reduce levels of ammonia formed in the brain, muscles and kidneys, as well as help balance the body’s nitrogen chemistry and prevent nitrogen excess in body tissues and fluids. Individuals with high protein intake or gastrointestinal microbiota imbalance may benefit from supplemental AKG to help balance ammonia levels and protect tissues.*

Designed to meet the needs of individuals who require additional amino acids for protein support. This formulation of 20 essential and non-essential “L-form” amino acids uses the highest-quality, pharmaceutical grade, crystalline amino acids in their “free” form to ensure maximum bioavailability and tolerance. Amino Acid Complete supports GI health, the repair and rebuild of healthy muscle and connective tissue, and provides essential nutrients for healthy hair, skin, and nails.*

BiotaGen® is a distinctive formulation of soluble dietary fiber with prebiotic activities that stimulates growth of colonic populations of beneficial bacteria and supports gastrointestinal and systemic immune function.* BiotaGen® combines chicory inulin with larch arabinogalactan and purified yeast beta-glucan.*_x000D_ _x000D_ BiotaGen® is recommended to nutritionally support optimal gastrointestinal function, promote populations of healthful colonic bacteria, and support gastrointestinal and systemic immune function.* BiotaGen® works synergistically with probiotics to help assure intestinal microbiota balance.*

Spore-forming bacilli have often been referred to as soil-based microorganisms because of their ubiquitous presence in the earth. When isolated from the human GI tract, spore-forming bacilli have long been thought to be transient bacteria. However, current research shows that Bacillus species are present in the GI tract in numbers higher than can be explained by ingestion alone. Germination of Bacillus spores within the human small intestine and transient colonization is now thought to be part of the normal life cycle of human-associated Bacillus species providing specific stimuli for healthy GI and immune system development and function. Each capsule of BioSpora™ supplies a total of 2 billion CFUs of B. coagulans and B. subtilis spores positively identified through independent 16S ribosomal RNA gene sequencing. The spores are resistant to extremes of heat, ultraviolet radiation, solvents, hydrogen peroxide, and enzymes. The spores withstand stomach acid and germinate in the small intestine within 6 hours of ingestion. Ingested B. coagulans and B. subtilis reside in the human GI tract for up to 7 days following consumption. BioSpora™ is recommended for enhanced support of normal GI and immune function.* It is certified free of casein, gluten, and soy. BioSpora™ does not require refrigeration.

The heart muscle, periodontal tissues, immune system, liver, kidney, brain, and other vital organs require coenzyme Q10 to supply energy through ATP activation and to help protect them from free radicals.* Illness, aging, poor nutrient intake, and use of certain medications can result in inadequate endogenous production of CoQ10 to sustain optimal organ function. Each vegetarian capsule provides 100 mg of pure ubiquinone.

An extensively studied curcumin extract, Meriva® has 18 times higher bioavailability of curcumin and 29 times higher relative absorption of total curcuminoids vs. standardized curcumin. Curcuthera’s patented Phytosome® delivery system allows for enhanced absorption and utilization of curcumin to support a balanced and healthy inflammatory response and provides powerful antioxidant activity.* Hypoallergenic. Made with non-GMO ingredients. Vegan Friendly

Each batch of Eicosamax TG is responsibly and sustainably harvested and independently tested for mercury, pesticides, and PCBs to assure exceptional oil purity. Anaerobic bottling, natural lemon flavoring, as well as added mixed tocopherol antioxidants protect against oxidation, maintain product freshness, and ensure a fresh, non-fishy taste. Eicosamax TG supplies 360 mg of EPA and 240 mg of DHA per softgel.

Each batch of Eicosamax TG is responsibly and sustainably harvested and independently tested for mercury, pesticides, and PCBs to assure exceptional oil purity. Anaerobic bottling, natural lemon flavoring, as well as added mixed tocopherol antioxidants protect against oxidation, maintain product freshness, and ensure a fresh, non-fishy taste. Eicosamax TG Liquid supplies 1,400 mg of EPA and 925 mg of DHA per teaspoon. Eicosamax® TG supplies highly-concentrated amounts of important omega-3 EPA and DHA fatty acids in triglyceride form, derived from fish oils. Molecular distillation processing and state of the art purification technologies yield an ultra-pure fish oil concentrate. Each batch is independently tested for mercury, pesticides, and PCBs to assure exceptional oil purity. Added antioxidants (natural mixed tocopherols, rosemary extract, ascorbyl palmitate) maintain freshness by protecting against oxidation. Natural lemon flavor provides a light citrus taste.

The seed oil of Evening Primrose (Oenothera biennis) provides gamma-linolenic acid (GLA), an essential omega-6 fatty acid. Cold-pressed without hexane or other solvents, these softgels contain 76 mg of biologically active GLA. Evening primrose supports cartilage and joint function, neuroendocrine and cognitive health, skin and connective tissue health, and helps maintain nerve function, and cardiovascular health.*

InterFase® Plus combines the same unique enzyme formulation found in InterFase® with ethylenediaminetetraacetic acid (EDTA). The presence of calcium, iron, and magnesium is essential for biofilm creation and serves to cross-link the anionic regions of polymers. InterFase® Plus includes EDTA which binds the metals needed for biofilm formation. InterFase® Plus can be used for maximum antibiofilm activity.*

Iodine is an essential element. Although its main function is in the production of thyroid hormones T3 and T4, other organs in the body have a need for iodine in order to function normally.

Iodine is an essential element. Although its main function is in the production of thyroid hormones T3 and T4, other organs in the body have a need for iodine in order to function normally.

BioCell Collagen® is a concentrated source of bioavailable, hydrolyzed collagen type II, chondroitin sulfate, and hyaluronic acid. A patented process produces a low molecular weight mixture of components that are easily absorbed and readily available for use in the body to protect connective tissues, promote cartilage synthesis, support repair, and improve the overall appearance of the skin.* Hyaluronic acid is an important nourishing agent that helps to retain the natural moisture content of skin tissue and joint fluids.* Chondroitin sulfate supports synthesis of cartilage tissue and inhibits cartilage-degrading enzymes.* OptiMSM®, a sulfur and methyl donor, supports joint structure and comfort. Vitamin C is required for hydroxylation, a biochemical process required for cartilage synthesis.

L-glutamine is a conditionally essential amino acid and primary energy source for intestinal cells. It is also a major amino acid in muscle tissue. The body’s ability to produce adequate amounts may be compromised during physiological stress, thus warranting supplementation.

Glutamine, the most abundant amino acid in the body, helps form other amino acids, glucose, protein, and glutathione. Glutamine is stored in the muscles and is the primary metabolic fuel for the cells of the small intestine, fibroblasts, and the immune system.* Supplementation with glutamine can help support gut cell proliferation and mucosal integrity, resulting in decreased intestinal permeability and healthy immune function.*

This broad-spectrum, 12-strain blend of 7 Lactobacillus and 5 Bifidobacterium species is provided in a base of purified plant cellulose. This formula is free of inulin and other prebiotics and polysaccharides making it suitable for those who have dietary restrictions.- Multi-Species - Probiotic Supplement

Magnesium helps convert carbohydrates, protein, and fats to energy, acts as a catalyst in thousands of enzymatic processes, regulates and maintains vascular tone, opposes calcium deposition into soft tissue, and is critical to proper bone formation.* It regulates calcium and potassium metabolism, facilitates muscle constriction and relaxation, and assists in nerve transmission and conduction.* For optimal absorption, this formulation uses magnesium combined with amino acid glycine to create a unique chelated compound that is highly bioavailable and well tolerated by even the most sensitive individuals.

This formulation combines two forms of vitamin A—palmitate and betacarotene—that have been micellized into extremely small droplets that are easily absorbed into the bloodstream. Potassium sorbate provides a safe, well-tolerated, and hypoallergenic stabilizing agent for the liquid Micellized Vitamin A preparation. Each drop supplies 1,507 mcg RAE of vitamin A.

Glutathione is a powerful antioxidant and detoxifying compound consisting of three amino acids: cysteine, glutamic acid, and glycine.* Produced in the liver, glutathione assists with detoxifying xenobiotics and metals, neutralizes hydrogen peroxide, maintains the integrity of blood cells, and helps transport amino acids across cell membranes.* These hypoallergenic formulations have been specifically designed using the active, reduced form of glutathione for maximum benefit.

S. boulardii increases the activities of intestinal brush border enzymes such as disaccharidases, a-glucosidases, alkaline phosphatases, and aminopeptidases.* S. boulardii augments the intestinal absorption of D-glucose coupled with sodium that may enhance uptake of water and electrolytes during occasional diarrhea.* It increases stool concentrations of short-chain fatty acids that nourish colon mucosal cells.* S. boulardii modulates immunity by boosting intestinal secretion of IgA and increasing crypt cell immunoglobulin receptors.* It supports healthy inflammatory response.* Research has found that S. boulardii supports healthy intestinal function in an array of clinical settings, supporting healthy bowel transit time. Klaire Labs® S. Boulardii is American Type Culture Collection (ATCC) certified and freeze-dried to maintain maximum strength and viability. Klaire uses only lactose-free, gluten-free material. This hypoallergenic formula is available in vegetarian capsules. S. boulardii is also an important ingredient in ABx Support™, supplying 250 mg (5 billion CFUs).

S. boulardii increases the activities of intestinal brush border enzymes such as disaccharidases, a-glucosidases, alkaline phosphatases, and aminopeptidases.* S. boulardii augments the intestinal absorption of D-glucose coupled with sodium that may enhance uptake of water and electrolytes during occasional diarrhea.* It increases stool concentrations of short-chain fatty acids that nourish colon mucosal cells.* S. boulardii modulates immunity by boosting intestinal secretion of IgA and increasing crypt cell immunoglobulin receptors.* It supports healthy inflammatory response.* Research has found that S. boulardii supports healthy intestinal function in an array of clinical settings, supporting healthy bowel transit time. Klaire Labs® S. Boulardii is American Type Culture Collection (ATCC) certified and freeze-dried to maintain maximum strength and viability. Klaire uses only lactose-free, gluten-free material. This hypoallergenic formula is available in vegetarian capsules. S. boulardii is also an important ingredient in ABx Support™, supplying 250 mg (5 billion CFUs).

An impressive amount of research and long history of clinical use documents the benefits of SAMe. As a modulator of cell membrane fluidity and neurochemical activity in the central nervous system, it helps support mood and optimal brain function.* The sulfur in SAMe is used to help build cartilage and strong joints and for synthesis of taurine and glutathione, used in liver detoxification processes.* SAMe also helps synthesize polyamines required for normal cell growth.* The reactive nature of SAMe prevents it from being used in combination nutrient products, but it can be stabilized as a single ingredient with careful manufacturing and an enteric tablet coating. This product provides a pharmaceutical grade, stabilized SAMe manufactured under low temperature and low humidity conditions. An enteric tablet coating is applied to further ensure a biologically active product. Each tablet contains a full 200 mg of elemental SAMe from 400 mg SAMe tosylate disulfate. These enteric extended release tablets offer improved delivery and comply with or exceeed the standards established by the United States Pharmacopeia (USP). Slow-release coating technology optimizes stability in the stomach and enhances direct release and absorption in the small intestine. SAMe (S-adenosylmethionine) is a derivative of the essential amino acid L-methionine and is formed by combining ATP with L-methionine. SAMe is a chiral molecule and consists of two stereoisomers: (S,S) and (R,S). This SAMe has a high level (65%) of the (S,S) isomer, the biologically active form. Some of the reported beneficial actions of SAMe include: Joint and Connective Tissue Strength: SAMe supports production of healthy connective tissue and joint structures by contributing its sulfur component for transulfuration processes that help form glucosamine and chondroitin sulfates, critical components of connective tissues.* Brain Metabolism: SAMe serves as a major source of methyl groups used by the brain in the synthesis of neurotransmitters such as serotonin, L-dopa, dopamine, and related hormones involved in mood regulation.* Liver Function: Metabolism of SAMe supports synthesis of glutathione and glutathione-dependant enzymes (glutathione peroxidase and glutathione-S-transferase), which are important antioxidants used in liver detoxification processes.*

Selenium also serves as an antioxidant by activating glutathione peroxidase, an antioxidant enzyme that protects cell membranes from free radicals.* Seleno Met™ uses L-selenomethionine, a highly bioavailable, yeast-free form of organically bound selenium chelated with methionine to support glutathione activity. Unlike inorganic forms of selenium, Seleno Met™ is not adversely affected by vitamin C.

Ther-Biotic® Complete is a robust, broad-spectrum, hypoallergenic blend of 12 probiotic species in a base of inulin. Designed to supply a complete component of synergistic and complementary species, each capsule provides 25 billion CFU protected by our proprietary InTactic® technology for maximum viability throughout the intestinal tract. Available in 25B CFU capsules or 100B CFU powder Probiotic Mechanisms Competitive and antagonistic activity against undesirable microorganisms* Strengthening of intestinal epithelial barrier integrity* Short chain fatty acid production nourishes enterocytes* Healthy inflammation balance* Support of innate and acquired immunity*

Ther-Biotic® Complete is a robust, broad-spectrum, hypoallergenic blend of 12 probiotic species in a base of inulin. Designed to supply a complete component of synergistic and complementary species, each capsule provides 25 billion CFU protected by our proprietary InTactic® technology for maximum viability throughout the intestinal tract. Available in 25B CFU capsules or 100B CFU powder Probiotic Mechanisms Competitive and antagonistic activity against undesirable microorganisms* Strengthening of intestinal epithelial barrier integrity* Short chain fatty acid production nourishes enterocytes* Healthy inflammation balance* Support of innate and acquired immunity*

Ther-Biotic® Complete is a robust, broad-spectrum, hypoallergenic blend of 12 probiotic species in a base of inulin. Designed to supply a complete component of synergistic and complementary species, each 0.25 teaspoon (1 gram) provides 100 billion CFU protected by our proprietary InTactic® technology for maximum viability throughout the intestinal tract. Available in 100B CFU powder or 25B CFU capsules Probiotic Mechanisms Competitive and antagonistic activity against undesirable microorganisms* Strengthening of intestinal epithelial barrier integrity* Short chain fatty acid production nourishes enterocytes* Healthy inflammation balance* Support of innate and acquired immunity*

Ther-Biotic® Detoxification Support is a concentrated 3 species blend, in a cellulose base, specifically designed to complement detoxification protocols from agents that can compromise beneficial bacteria.* Selected species support detoxification by digesting endotoxins and reducing toxin uptake through tight junction intestinal barrier support.* Each capsule provides 50 billion CFU protected by our proprietary InTactic®technology for maximum viability throughout the intestinal tract.

Ther-Biotic® Children’s Chewable is a broad-spectrum, hypoallergenic probiotic supplement designed for children 2 years of age and older. Our 25 billion CFU formulation, in a base of inulin, contains eight total Lactobacillus and Bifidobacterium species which have been intensively researched and clinically shown to support gastrointestinal health and immune function in children.* The natural cherry flavor makes daily supplementation easy.

Ther-Biotic® Women’s Formula is a hypoallergenic blend of 10 species, in an inulin base, specifically designed to support a woman’s genitourinary system.* Concentrated with Lactobacilli, secreted biosurfactants, and lactic acid promote a healthy vaginal pH.* Each capsule provides 25 billion CFU protected by our proprietary InTactic®technology for maximum viability throughout the intestinal tract. Hypoallergenic

Vitamin K is an essential nutrient, best known for its role in normal blood clotting.* Vitamin K, specifically in the form of vitamin K2 such as menatetrenone and menaquinone-7, supports cardiovascular, bone, and connective tissue health.*

This blend of 3 Lactobacillus and 1 important Bifidobacterium species assists growth and maintenance of beneficial bacteria that support immune system function.* The Lactobacillus species colonize and protect the small intestine and lower the luminal pH, creating conditions that allow B. longum to efficiently colonize the colon.* Together, the Lactobacillus species and B. longum enhance innate and acquired immunity, modulate immune tolerance, support healthy inflammation metabolism, increase the number of intestinal IgA-producing cells, and augment gastrointestinal immune responsiveness to undesirable microorganisms while promoting tolerance to environmental stimuli.*- Multi-Species - Non-Dairy - Maltodextrin-Free - Certified Strains

The enzymes in Vital-Zymes Forté provide maintenance-level support of digestive and intestinal health.* Mid-range amounts of lactase (dairy/lactose-specific) and alpha-galactosidase (legume-specific) are included to suit individuals who have difficulty digesting these foods.* Use of plant-based and microbial enzymes in this formulation provides multi-enzyme activity across the broad range of pH conditions (pH of 2 to 12) found throughout the intestinal tract.*

Formulated using the same enzymes contained in Vital-Zymes Complete with the exclusion of lysozyme, Vital-Zymes Chewable is a good choice for administering enzymes to children or adults who may prefer a chewable tablet. This broad-spectrum enzyme formulation has moderate amounts of enzymes compared to Vital-Zymes Complete to allow it to be comfortably chewed for routine daily use or as needed. Vital-Zymes Chewable can assist in the breakdown of a wide range of proteins, peptides, fats, complex carbohydrates, sugars, and fibers.† Serratia peptidase, a unique endopeptidase enzyme, helps protect sensitive GI tissue from irritation that can affect tissue health and intestinal comfort.† Enzymes with DPP-IV activity and a full range of disaccharidases are included.*

Vitamin A is an essential nutrient for healthy immune function.* Vitamin A is also essential to eye health.* Diets that are deficient in vitamin A are now common because of poor dietary habits and the depletion of vitamin A in processed foods., , Other important functions of vitamin A include supporting healthy bone growth, normal cellular differentiation and growth, and healthy skin.*

Active forms of folate, B12, and B6 along with naturally sourced carotenes, vitamin E tocopherols, and vitamin D3 are included for optimal nutrient absorption and utilization. Iron and copper, often contraindicated for people on the spectrum, are excluded. This formula is similar to VitaSpectrum® Powder but the amounts of calcium and magnesium have been reduced to ensure the formula will fit in 6 medium-size capsules. Supplied in two-piece vegetarian capsules made from purified cellulose.

VitaSpectrum® addresses these inadequacies by supplying balanced amounts of vitamins, minerals, and trace elements in forms that are typically well tolerated by those on the spectrum. Bioactive forms of folate, B12, and B6 are included along with naturally sourced carotenes, vitamin E, and D for optimal nutrient absorption and utilization. Iron and copper, often contraindicated in those on the spectrum, are excluded. VitaSpectrum® is free of common allergens, including milk/casein, eggs, fish, shellfish, tree nuts, peanuts, and wheat/ gluten. No starch, maltodextrin, stearates, artificial sweeteners, colors, flavors, or preservatives are used. VitaSpectrum® formulas comply with Gluten-Free/Casein-Free (GFCF) diets. For maximum tolerance and versatility as a foundational nutritional program, herbal ingredients are avoided. The pleasant, natural berry-pomegranate or citrus flavored powder formulas dissolve easily in liquids or can be mixed in foods. A convenient measuring scoop is provided for accurate measurement. Hypoallergenic multiple vitamin/mineral supplement in powder form containing 28 highly bioavailable essential nutrients designed to address nutritional imbalances commonly observed in children on the spectrum. Well-tolerated ingredients are used for optimal nutrient absorption and utilization.

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